HER1 signaling is triggered by individual HER1 monomers each binding to its ligand followed by homodimerization and autophosphorylation. How do HER2/HER3 heterodimers initiate signaling?
A. Neither HER2 nor HER3 bind ligands, but can form heterodimers that activate HER2 tyrosine kinase which creates a GRB2 binding site.
B. Neither HER2 nor HER3 bind ligands, but can form heterodimers that activate HER2 tyrosine kinase which creates a GRB2 binding site.
C. HER2 and HER3 monomers each bind to its ligand followed by heterodimerization and activation of both HER2 and HER3 tyrosine kinases which create a GRB2 binding site.
D. HER2, but not HER3 binds to its ligand, causing it heterodimerize with HER3. This activates HER3 tyrosine kinase which creates a GRB2 binding site.
E. HER3, but not HER2 binds to its ligand, causing it heterodimerize with HER2. This activates HER2 tyrosine kinase which creates a GRB2 binding site.

Answers

Answer 1

Answer:

E. HER3, but not HER2 binds to its ligand, causing it heterodimerize with HER2. This activates HER2 tyrosine kinase which creates a GRB2 binding site.

Explanation:

The receptor tyrosine-protein kinase, also known as human epidermal growth factor receptor 3 (HER3), is a transmembrane tyrosine kinase receptor that doesn't have a kinase domain. HER3 binds to the HER2 protein (another receptor tyrosine kinase receptor) to form a heterodimeric complex. Conversely to the HER3 protein, HER2 lacks a ligand-binding domain. The HER2/HER3 complex triggers the activation of the HER2 kinase domain which then autophosphorylates and thus generates a binding site for the Growth factor receptor-bound protein 2 (Grb2).

Answer 2

2 3x 67 4 y ^6 29 = 7 y ^2 8720 [t + X]


Related Questions

Compare and contrast inexhaustible and renewable resources. Plz help I’m despreat

Answers

Answer:

Compare and contrast inexhaustible and renewable resources. Inexhaustible resources are sources of energy that will never run out. In contrast, renewable resources could potentially run out. They are finite energy resources that can be replaced in a relatively short period of time.

Explanation:

Which term means "surgical
creation of a new opening to the
outside from the windpipe"?
A laryngectomy
B. tracheotomy
D. tracheostomy

Answers

Answer: D. Tracheostomy

Explanation: hope this helps
It’s D because that is the only one that makes completely since

Continue building the strand of mRNA until you have used all of the RNA nucleotides. What is the nucleotide sequence of the mRNA strand you built?

Answers

Answer:

This question is incomplete

Explanation:

However, mRNA can be built from a DNA sequence; i.e a DNA strand is used as a template for the production of an mRNA sequence. This process occurs during transcription. While the four nitrogenous bases in a DNA molecule are adenine, thymine, guanine and cytosine, in RNA the thymine is absent and replaced with uracil. While producing the mRNA strand, Uracil will be complementary to adenine, adenine will be complementary to thymine, guanine will be complementary to cytosine and cytosine will be complementary to guanine. This can be seen in the illustration below:

DNA sequence:    T--G--G--C--A--G--C--T--A--C--C--G

mRNA sequence:     A--C--C--G--U--C--G--A--U--G--G--C

Thus, while building a mRNA nucleotide sequence, the procedure above can be followed

5. How are Stages 1 and 4 of demographic transition model above similar?

Answers

Answer:

They ain't similar in any way but are entirely opposite to each other because the stage 1 has a high rate of birth and death while the stage 4 has a low rate of birth and death

Some salmon have been genetically modified to grow bigger and faster than wild salmon. They are grown in fish-farming facilities. These genetically modified fish should not be introduced into a natural habitat because
A)
the salmon would recycle nutrients at a rapid rate

B)
their rapid growth rate could cause them to outcompete native salmon

C)
they would not have enough oxygen for survival

D)
they would reproduce asexually once they were released

Answers

Answer:

B

Explanation:

Their growth rate would cause them to grow much larger than the native salmon meaning they require more habitat space and sustenance to live. This would drive out the native salmon as they wrestle for food and space.

Which statement explains why many scientists believe that carbon dioxide has likely contributed more to global warming than other greenhouse gases?

Carbon dioxide is emitted from fertilizers used in farming.
Other greenhouse gases trap more heat than carbon dioxide.
Carbon dioxide has increased as a result of increased human activities.
Carbon dioxide is emitted from commercial refrigeration.

Answers

Answer:

C. Carbon dioxide has increased as a result of increased human activities.

I got it correct on my Quiz!!

GIVE THE OTHER PERSON WHO ANSWER THIS QUESTION CREDIT!!!

CO₂ is a gas that composes the atmosphere, but its increase contributes to the greenhouse effect. C)CO₂ has increased as a result of increased human activities.

What is CO₂, and how does it affect the greenhouse effect?

Carbon dioxide (CO₂) is a gas that, among other gases, composes the atmosphere, mainly the troposphere, which is closest to the Earth.

The balance of this gas in nature is very complex and involves interactions between the atmosphere, the plants, and the oceans.

CO₂ is essential for plants to photosynthesize. Photosynthesis transforms CO₂ into organic compounds and releases oxygen as final products together with carbohydrates.

This gas is not nocive at concentrations between 300 and 500 ppm. However, the current increase in CO₂ is a responsible component of the greenhouse effect involved in global warming and climate change. The rise in CO₂ is possibly the best documented.

The atmospheric increase of CO₂ follows a natural fluctuation trend that has been happening throughout the whole of Earth's history.

It has been proven that the current rise in CO₂ concentration overlaps the expected variation and that the reached levels at the moment exceed the highest past registered levels. This substantial increase must be related to human activities, such as forest destruction, industry, and fossil fuel uses, among many others.

The correct option is C. Carbon dioxide has increased as a result of increased human activities.

You can learn more about carbon dioxide at

https://brainly.com/question/17212397

https://brainly.com/question/14452716

Two species of meadowlarks have different mating calls that lead to reproductive isolation. What type of isolation does this example represent?
A.
mechanical
B.
behavioral
C.
temporal
D.
gametic

Answers

answer : C
Because according to google behaviors

Answer:

B. behavioral

Explanation:

plato

Valence electrons=____

Answers

Explanation:

not sure if you are wanting the definition of Valance electrons, but if you are a simple explanation woulf be, "an outer shell electron that is associated with an atom, that can participate in the formation of a chemical bond".

Answer:

the electrons located in the outer shell of an atom that can take part in chemical reaction also are known as valence electrons in simple form .

hope this helped you .

Infectious diseases are caused by?

A.Pathogens
B.vaccines
C.Antibodies
D.Minerals ​

Answers

Infectious diseases are disorders caused by organisms — such as bacteria, viruses, fungi or parasites. Many organisms live in and on our bodies.

Match each description with the appropriate term listed
Fungi
Viruses
Bacteria
Protozoans

Answers

Explanation:

they all are microorganisms and are different kind of category....

What monomer is needed to speed up chemical
reactions?

Answers

Answer:

Enzymes

Explanation:

Proteins are polymers made up of ammo acids. Enzymes are a category of proteins. They are catalysts. They speed up the rate of a chemical reaction.

Which of the following elements makes up the tissues and organs of animals? Carbon Hydrogen Nitrogen Oxygen

Answers

Answer:Carbon

Explanation:

Carbon is one of the most important elements for the structure of living things. It is responsible for 19% of the body composition of animals, behind only oxygen, which contributes 61%. The head is one of the main elements that make up the tissues and organs of animals.

Answer:

carbon

Explanation:

i took the test

A human blood cell is placed in fresh water. As a result, water moves _____ the cell

Answers

Answer:

inside

Explanation:

osmosis is where water moves from high water conservation(outside of the cell) to a low water concentration(inside the cell) through the memebrane.

Answer:

the blood cell will burst in fresh water

Explanation:

Pls help me ASAP Plsssssssssssddd

Answers

Answer:

Older rock layers are found under younger rock layers

Explanation:

It directly states in the sentence above the diagram that the bottom layer of rock is the oldest.

Based on the information presented what can the students conclude about what caused the disturbance in this forest community?
secondary succession after a fire
O primary succession after a mudslide
O primary succession after a volcanic eruption
O Secondary succession after a glacier recedes

Answers

Answer: A. secondary succession after a fire.

Explanation: The graph shows a disturbance and then the ecosystem rebuilding itself which would mean it goes through secondary succession.

Curly hair (C) is dominant to straight hair (c). What must the genotype of the parents be to produce CC Cc CC Cc

Answers

Answer:

Expected frequency of CC genotype:      

✔ 0.01

Expected frequency of Cc genotype:            

✔ 0.18

Expected frequency of cc genotype:            

✔ 0.81

Explanation:

Which process allows water to enter the atmosphere?
evaporation
condensation
precipitation
freezing

Answers

Answer:

Evaporation allows water to enter the atmosphere.

Explanation:

Answer:

You answer would be A.) Evaporation

Explanation:

Just did the test

Edge2021

PLZZZZZ hELP
When light passes from one medium to another, it bends. This phenomenon is
known as what?
reflection
refraction
subtraction
distraction

Answers

answer is refraction .

The organelle that is a major producer of ATP and is found in both heterotrophs and autotrophs is the

Answers

Mitochondria is the answer to your questions

A major influence on climate is?

Answers

Answer:

that's very broad, is that the whole question?

Answer:

A major influenece is the wide and used fossil fuels

what will happen as a result of the cold front coming in contact with a warm front?

Answers

An occluded front occurs which forces the warm air above the cooler air

Answer:

When a cold front overtakes a warm front, it creates what's called an occluded front that forces warm air above a frontal boundary of cooler air masses.

Explanation:

what type of pigment is located in the membrane of the thylakoid

Answers

Answer:

The green pigment chlorophyll is located within the thylakoid membrane, and the space between the thylakoid and the chloroplast membranes is called the stroma.

Explanation:

Answer:

green pigment chlorophyll

Explanation:

the green pigment chlorophyll is located within the Thylakoid membrane, and the space between the thylakiod the and chloroplast membranes is called the storma

The cell cycle of yeast cells grown in the nutrient-poor environment is approximately what percent of the cell cycle of yeast cells grown in the nutrient-rich environment.

Answers

Answer: 168

Explanation:

The cell cycle of yeast cells grown in the nutrient-poor environment is approximately 168 % of the cell cycle of yeast cells grown in the nutrient-rich environment. Hence option 1 is correct.

What is cell cycle?

Cell cycle is defined as the cascade of cellular activities that lead to cell division into two daughter cells. The primary purpose of the cell cycle is to accurately divide the enormous amount of DNA found in the chromosomes into two daughter cells that are genetically identical. A cell spends the majority of its time in what is known as interphase, where it develops, duplicates its chromosomes, and gets ready to divide.

The interphase and M-phase are the two phases that make up the cell cycle. About 90% of the cycle is made up of interphase, during which the cell develops and copies its chromosomes in order to divide. Undifferentiated ESCs have a G1 and S cell cycle percentage of 15-20% and 60–70%, respectively, however as the ESCs differentiate, this ratio changes.

Thus, the cell cycle of yeast cells grown in the nutrient-poor environment is approximately 168 % of the cell cycle of yeast cells grown in the nutrient-rich environment. Hence option 1 is correct.

To learn more about cell cycle, refer to the link below:

https://brainly.com/question/15876101

#SPJ2

1.Igneous rock is where new rock is formed from molten
2. The slower the magma cooks the larger the___ are on the surface of the rock.
3. Every sedimentary rock come from?
4. Metamorphic rock occurs when you take another type of rock and put them under ____ and ___ and they twist and meld together
5. In the rock cycle, if any type of rock is broken down into little pieces, it changes into___ rock

Can someone help me plz plz pls plz plz tysmmmmm to the person who help me

Answers

Answer:

1. lava

2. crystals

3. rivers, deposition, weathering

4. heat and pressure

5. Sedimentary rocks

Explanation:

1. igneous rocks from from lava, hence, the name

2. magma forms crystals, so the process at which they melt alters the sizes

3. sedimentary rocks occur due to extreme pressure over time, such as weathering, or rain

4. heat and pressure for a long period of time can melt and from new rocks

5. Sedimentary rocks from from pieces of other rocks

Which of the following is not associated with the light-driven reactions?
Biology

Answers

Answer:

soil,air and water

Explanation:

give nutrients to plants and release oxygen

Most Sequoias are found in which state__________________?

Answers

Answer:

Northern California

Explanation:

Which one of the following is associated with bacterial cells?
Select one:
o
a. Ribosomes
b. Nucleus
c. Lysosomes
d. Mitochondria
e. Smooth endoplasmic reticulum​

Answers

Answer:

a) Ribosomes

Explanation:

Ribosomes are organelles that initiate protein synthesis in cells. Both Eukaryotes and prokaryotes encompass ribosomes with them. However, They are structurally different in Eukaryotes and prokaryotes such as Bacterial Cells.

multiple choice
this major site of protein synthesis has ribosomes attached to it and protects proteins within its folds from being exposed to the cell’s internal environment.

a. rough endoplasmic reticulum
b. smooth endoplasmic reticulum
c. golgi apparatus

Answers

Answer:

Its a

Rough endoplasmic rectulum

Or RER.

What would be the most appropriate conclusion for this experiment? I NEED ASAP DUE TODAY!! THANKSSS :D

Answers

Answer:

It is D

Explanation:

It says it was summerized after three weeks.

It is D

Your welcome might as well put a thank you in my profile :)

why do microorganisms interact

Answers

Answer:

it is frequently related to pathogenic or beneficial effect to host

Explanation:

it is an important role

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