2. What influence does the FBP1 protein have on the cell cycle and how can this proliferate the cancer

Answers

Answer 1

Answer:

FBP1 promotes cancer by accelerating the transition of cell cycle from G1 to S and G2 stages

Explanation:

The far-upstream element (Fuse)-binding protein 1(FBP1) is an oncoprotein that is overexpressed in different types of cancers such as, for example, hepatocellular carcinoma, ovarian cancer, etc. It is known that FBP1 binds to the tumor suppressor gene p53 and thus suppresses its transcription. Moreover, in ovarian cancer, it has been shown that the inactivation or 'knockdown' of FBP1 inhibits cell cycle transition from G1 (the first phase of the cell cycle during cell division) to S and G2 phase. The cyclin D1/E and c-Myc proteins which are required for the progression of cells through the cell cycle were found to be inhibited in FBP1-knockdown cells.


Related Questions

Wombats are mammals with a gestation period of about
20 days. At birth, the baby wombat, called a joey, is tiny
and hairless. It crawls into its mother's external pouch
where it continues to develop for about eight months.

Based on this information, wombats are classified as
______mammals.

Answers

Answer:

marsupials

Explanation:

Which of the following require clear warning signs or labels? Check all that apply

Answers

The options that would clearly require the use of warnings would be:

Places where a spill was recently cleanedContainers with bodily fluids

What is a warning sign?

This is the term that is used to refer to the signs that are placed in objects so that it would serve as precaution to the people around who may come in contact with those objects.

The goal of the warning sign is to ensure that people do not suffer un desirable consequences when they get in contact with these items which may have the potentials of causing them harm.

For instance bodily fluids that are infected may be harmful to other people hence the need to ensure that it is well protected and has all of the right labels on it.

Also area that spills have occurred may be radioactive area as and they may be dangerous to the health of persons that go near them.

Read more on warning sign here: https://brainly.com/question/15508781

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Answer:C,D

Explanation:

PLEASE ANSWER ASAP WILL MARK BRAINLIEST:
A region experiences frequent landslides from heavy rains. How can the local residents lower the frequency of landslides in the region?

Answers

Plant vegetation is the best answer, if multiple then also do the deforestation (not 100% sure ok the deforestation one)

B. Plant vegetation on the slops that expreience landslides.

E. Reduce the sloped where landslides occur.

Hope this helped, please mark brainiest!

In order for a male to have
the recessive disease, what
would his genotype be?

Answers

A sick man would have the genotype aa, if the illness is on the recessive gene (a). Aa and AA would be a healthy person, because the A is dominant.
But I really don't understand the relevance of the person being male in this context

Thermohaline circulation supplies heat to polar

Answers

Answer:

Your are correct.

What event might occur when favorable adaptations build up in a population over many generations?
starvation
extinction
migration
speciation

will give brainlist ​

Answers

Speciation. I am learning this in class too. This is the definition of speciation: “the formation of new and distinct species in the course of evolution” :)

Answer:

D. speciation

Explanation:

Over many generations, these favorable adaptations build up in a population. This may lead to speciation, which is the development of a new species.

What does the circulatory
and respiratory systems do?

Answers

Answer:

The respiratory system works directly with the circulatory system to provide oxygen to the body. Oxygen taken in from the respiratory system moves into blood vessels that then circulate oxygen-rich blood to tissues and cells.

Explanation:

1.
What is evolution?

Answers

Answer:

Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes that are passed on from parent to offspring during reproduction.

Explanation:

Rain forests are home to many of the largest animals on Earth.

True
False

Answers

Answer:

True

Explanation:

new nerve pathways are shaped by

experience
glucose
oxygen
blood

Answers

Answer:

oxygen....

Explanation:

hope this helps ✌

Help with these two ?

Answers

the first one is water and the second is carbohydrates

Dinitrophenol (2,4-DNP) destroys proton gradients without affecting anything else about a membrane. Its pKa slightly acidic, so it can be protonated or unprotonated in cells.a. What would be the effect of adding dinitrophenol to the mitochondrial inner membrane

Answers

Answer:

the effect of adding dinitrophenol to the mitochondrial inner membrane is -:

Production of ATPNo electron transferproduction of more sugar as energyUncoupling of ETC(electron transport chain)

Explanation:

Dinitrophenol is an uncoupler which can isolate the progression of electrons and siphoning of H+ particles for ATP Synthesis. On adding the dinitrophenol, the energy from the electron move can't be utilized for ATP blend. It has been utilized in diet pills and as a counting calories help. It goes about as protonophore and permits spillage of the protons through the internal mitochondrial layer which subsequently sidesteps ATP synthase and consequently the creation of ATP creation gets wasteful. It hinders the ATP synthase and thus its capacity to deliver ATP. It likewise influences the ETC in light of the fact that forestalls development of electrons over the ETC. Uncoupling the ETC would prompt diminished ATP creation and consequently increasingly more sugar is used as energy. This would restrict accessibility of ATP and make a deadly circumstance.

can wolfs have medicine?​

Answers

I believe they can have medicine

Answer:

Probably if it badly hurt then you would need it otherwise i think not.

Explain the process that creates wind.

Answers

Answer:

Winds are caused by differences in air pressure. Unequal heating of Earth’s surface creates areas of different pressure. Cooler areas have higher air pressure. Warmer areas have lower pressure. This causes air to move from high pressure to low pressure. This movement is the wind we feel.

Answer:

Wind is air in motion. It is produced by the uneven heating of the earths surface by the sun. since the earths surface is made of a various land and water formations, it absorbs the sun's radiation unevenly. Two factors are necessary to specify wind which is speed and direction.

Explanation:

7. _________________ consumers eat secondary consumers.

Answers

Primary is the answer
Primary consumers :)

What must match between a virus and a host cell?

A)DNA= Cell DNA
B)RNA=ribosome
C)envelope proteins= cell receptors
D)blood types

Answers

Answer:

C)envelope proteins= cell receptors

Explanation:

To enter the cell, the virus must bind to receptor proteins on the cell surface It does so via its envelope proteins. When the receptors and the envelope proteins match, the virus can become engulfed into the cell.

Once it enters the cell, the hijacks the cell's transcription and translation machinery and causes the viral proteins to be expressed. The viral proteins assemble into viral particles. Eventually, the cell bursts and the viral particles are released.

In "Close Encounters of the Bear Kind," what is the author's point of view toward bear researcher, John Hechtel?

Answers

Answer:

they are very facinating in there own way

Which factors involving the activities of people are a threat to biodiversity?

Answers

Answer:

a few factors include pollution, littering, hunting, poaching, and loss of habitat.

Which of the following is an example of commensalism?

Answers

Answer:

D. A bird builds a nest in a tree

Explanation:

The action above is only benefitting thee bird but not the tree but at the same time it is not hurting the tree. This is an example of commensalism.

What type of light is trapped in the Green House

Answers

Answer:

infrared light

Explanation:

The Earth absorbs this energy from the Sun and reemits it in the form of invisible infrared light. This energy is trapped by the greenhouse effect. Greenhouse gases have various shapes that make them effective at absorbing infrared radiation emitted by Earth.

It is a light called an infrared light.

Only the light in the visible spectrum can penetrate into the greenhouse whereas incoming infrared light, which is also known as heat radiation, is blocked by the glass or plastic.

To resist the ____ of gravity you have to pull on an object with more force than gravity.

Answers

Answer:

Pull

Explanation:

I think it's pull I'm 80% sure

What prevents a lake or ocean from freezing solid?

Answers

Answer:

The surface layer of the water freezes solid creating a barrier that insulates the ice below so that it keeps a steady temperature usually a few degrees above freezing (32 degrees).

Explanation:

What is the gradient formula?

Answers

Explanation:

The gradient of the line = (change in y-coordinate)/(change in x-coordinate) . We can, of course, use this to find the equation of the line. Since the line crosses the y-axis when y = 3, the equation of this graph is y = ½x + 3 . To find the gradient of a curve, you must draw an accurate sketch of the curve.

please help need now





What role do glucose and oxygen play in cellular respiration? O They are reactants because they are present before the reaction. They are reactants because they are present after the reaction. O They are products because they are present before the reaction. O They are products because they are present after the reaction. reagiging​

Answers

the first statement is correct

Answer:

They are reactants because they present before the reaction. Hope this helps!

Explanation:

I took the chapter test

Select the type of scientific communication that is best represented in each of the following examples.

An interactive exhibit about the human body at a science museum:

Four students working together to complete a biology laboratory experiment:

A poster presentation of a project at a school science fair:

An original research article published in a scientific journal:

A panel of scientists at a press conference answering questions about an oil spill:

A researcher at sea e-mailing the latest data to a fellow scientist at a university:

Answers

Answer:

1. Public

2. Classroom

3. Classroom

4. Professional

5. Public

6. Professional

Explanation:

Based on the given examples for scientific communication that is best represented, the answers are as follows:

1.Public

2. Classroom

3. Classroom

4. Professional

5. Public

6. Professional

Answer:

public

classroom

classroom

professional

public

professional

Explanation:

Which does not have scales?

amphibian
reptile
fish

Answers

Answer: amphibians

Explanation:

noice :3

An animal cell: the human body. Different but also alike. Your skin acts as the first line of defense against invaders. In this animal
cell, the
has a similar purpose.

A)
Golgi body

B
mitochondria

C
plasma membrane

D
endoplasmic reticulum

Answers

Answer:

Explanation:

C.

In this animal cell, the has a similar purpose as of skin is plasma membrane. The correct option is C.

What is plasma membrane?

The membrane that basically divides the interior of the cell from the external environment is known as the plasma membrane, sometimes known as the cell membrane, and it is present in all cells.

The cell membrane isolates a cell's interior contents from its external environment, just like your skin's outer layer does for your body and its surroundings.

The cell membrane acts as a barrier to protect it and controls what can enter and leave the cell.

One of the body's first lines of defense against hazardous germs is the skin, which acts as a barrier. Skin tissue contains specialized immune cells that aid in the defense against invaders.

The skin, however, is home to a variety of communities of helpful bacteria known as the skin microbiota.

Thus, the correct option is C.

For more details regarding plasma membrane, visit:

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Does mutualism involve abiotic or abiotic factors? Or both?

Answers

Let me look it up I’ll be back

Answer: Biotic factor


The muscle of the forearm that extends the digits is appropriately called the:
Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer.
a
Flexor carpi radialis
b
Biceps brachii
с
Extensor digitorum
d
Extensor carpi radialis longus

Answers

Answer:

Answer is letter C

Explanation:

The full name of this muscle is actually Extensor Digitorium Communus

The Digitorium part of its name also helps identify it.

Explain the similarities and differences between endocytosis and exocytosis, and give an example of each.

Answers

Similarities include: Both are involved in transporting big molecules across the membrane. ... formed from the cell membrane which then gets into the cytoplasm.Exocytosis increases the size of the cell membrane while endo does the opposite.

Other Questions
Explain how an author structures the text to develop connections and relationships or reveal authors purpose/point of view. The distance an electric car can travel on one full charge depends on the speed of the car. The table shows the approximate distances a certain model of electric car can travel on one full chargewhen moving at various constant speeds.The speed and the corresponding distance form an arithmetic sequence, where the speed represents the number of the term and the corresponding distance represents the value of the term.What is the distance, in miles, that the car can travel on one full charge when moving at a constant speed of 75 miles per hour (mph)?A) 220B250270D290 Reactivity of a_______ depends on how easily an electron(e-) can be removed. (This is lonization energy) Whitney sells cars at a local dealership. She receives a monthly salary of $904.00 and a $159.00 commission on each car she sells. If Whitney receives her commission check at the end of the month along with her salary check, which of the following equations can be used to determine her total pay for the month?(Let x represent the number of policies sold and y represent the total amount of pay for the month.) A. y = 904x + 159 B. y = 159x C. y = 159x + 904 D. y = 15.9x + 904 What kind of bond would two nonmetals typically make?A. An ionic bondB. A covalent bondC. A metallic bondD. An ionic solid Gorillas may look threatening, but they are peaceful and family-oriented animals. They are the largest of all primates, but as plant-eating animals, do not bother other creatures.Which choice best paraphrases the information? (5 points)Group of answer choicesGorillas may appear scary, but they are nonviolent and family-centered creatures. They are the biggest of all primates, but as vegetarian creatures, they do not inconvenience other species.As the largest primates, gorillas look imposing. In reality, they eat plants, protect their families, and keep to themselves.Gorillas look threatening but are peaceful and family oriented. They are the largest primate. They are plant eaters and don't bother other creatures.Gorillas are the largest of all primates. They may look threatening, but they are plant-eating animals. They are peaceful and family oriented and do not bother other creatures. Which generalization can be made from the data in the table? Which amendment provides individual freedoms? Two students Raymond and Shawna are trying to get city council members to vote for a new park along the river two six of the 24 council members say they already support the idea but that's not enough at least 13 council members must support the idea before the park is approved how many more City council Members must Raymond and Shawna convince A car is moving at an acceleration of 20 m/s^2 and hits a wall with a force of 400 N. What is the mass of the car? Hopefully someone understands this Select the correct branch described in each articleof the Constitution.Article I established thebranch.Article Il established thev branch.Article III established thebranch. Read the excerpt from Narrative of the Life of Frederick Douglass.If any one thing in my experience, more than another, served to deepen my conviction of the infernal character of slavery, and to fill me with unutterable loathing of slaveholders, it was their base ingratitude to my poor old grandmother. She had served my old master faithfully from youth to old age. She had been the source of all his wealth; she had peopled his plantation with slaves; she had become a great-grandmother in his service. She had rocked him in infancy, attended him in childhood, served him through life, and at his death wiped from his icy brow the cold death-sweat, and closed his eyes forever.Which line from this excerpt contains imagery?She had served my old master faithfully from youth to old age.She had been the source of all his wealth. . . .[S]he had become a great-grandmother in his service.[A]nd at his death wiped from his icy brow the cold death-sweat. . An office will increase salary to its top 8% employees on the basis of a performance score the office created for each employee. The performance score is approximately normal with mean 82.5 and standard deviation 9.25. How high must an employee score in order to qualify for increase in the salary? What type of energy is the energy of moving things?a. Mechanical b. Electromagneticc. Sound d. Thermal Write a hype about the use of an object physical characteristics to determine its density Write an equation in slope-intercept form for the line with slope 1/5 and y-intercept -8 What is 70 divisible by?? What is the author's viewpoint in "These Crows Almost Died Out Before Scientists Discovered They Use Tools"?A:The way that crows and humans use tools is very similar. B:The discovery of an animal that uses tools is an important event.C:Of the animals that use tools, crows are most skilled.D:Rutz may have found additional bird species that use tools if he had expanded his study.Question 2Part BHow is the viewpoint in Part A conveyed in the text?A:by explaining that studying tool use in animals could lead to finding a connection to tool use in humansB:by stating that Rutz was reluctant to search for bird species in remote areas because of the riskC:by comparing crows' behaviors with tools to behaviors in other tool-using speciesD:by describing how both crows and young children are naturally curious at birth 1and 2 are vertical angles. If the measure of 2 is 105, find the measure of1.